宏基因组检测帮助女子在神秘感染后保住视力
Metagenomics test saves woman's sight after mystery infection

原始链接: https://www.bbc.co.uk/news/articles/czx45vze0vyo

2019年,医学生艾丽的右眼出现炎症,最初被诊断为感染排除后的自身免疫性疾病。她被开了类固醇眼药水和免疫抑制剂,局部和静脉两种方式同时使用。这种强烈的治疗方案严重影响了她的生活,需要每小时滴一次眼药水,并阻碍了她作为实习医生的工作。她的视力波动不定,尽管使用了多种药物并进行了多次就诊,病情却没有任何好转。治疗和炎症导致她患上了白内障,毕业后不久便需要进行手术摘除。艾丽因为疾病和治疗的摧残性影响而达到了“崩溃边缘”。在绝望中,她甚至考虑摘除患病的眼睛,担心炎症会扩散到另一只眼睛。

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原文

In 2019, while still at medical school, Ellie began suffering from inflammation in her right eye. All tests for infection came back negative and it was assumed she had an autoimmune condition.

Ellie was prescribed steroid eye drops and immunosuppressants, some of which needed to be given by intravenous infusion.

"It was completely dominating my life," Ellie says. "I needed eye drops every single hour and it was difficult to balance that alongside starting work as a junior doctor. My vision was really variable, and I would have some bad days.

"I was on so much medication and going to so many appointments, yet I didn't feel I was getting any better."

The treatment and inflammation led to Ellie developing a cataract that had to be surgically removed, just after she graduated from medical school.

Ellie says she eventually reached "breaking point", and even began considering having her affected eye removed.

"Whilst losing sight in one eye is terrifying," she says, "my biggest fear was that it might spread to my left eye."

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