The research described here is a joint effort between many Google Research, Google Deepmind and Google Cloud AI teams. We thank our co-authors at Fleming Initiative and Imperial College London, Houston Methodist Hospital, Sequome, and Stanford University — José R Penadés, Tiago R D Costa, Vikram Dhillon, Eeshit Dhaval Vaishnav, Byron Lee, Jacob Blum and Gary Peltz. We appreciate Subhashini Venugopalan and Yun Liu for their detailed feedback on the manuscripts described here. We are also grateful to the many incredible scientists across institutions providing detailed technical and expert feedback — please refer to our report to see the voices and minds that aided this work. We also thank our teammates Resham Parikh, Taylor Goddu, Siyi Kou, Rachelle Sico, Amanda Ferber, Cat Kozlowski, Alison Lentz, KK Walker, Roma Ruparel, Jenn Sturgeon, Lauren Winer, Juanita Bawagan, Tori Milner, MK Blake, Kalyan Pamarthy for their support. Finally, we also thank John Platt, Michael Brenner, Zoubin Ghahramani, Dale Webster, Joelle Barral, Michael Howell, Susan Thomas, Jason Freidenfelds, Karen DeSalvo, Vladimir Vuskovic, Greg Corrado, Ronit Levavi Morad, Ali Eslami, Anna Koivuniemi, Royal Hansen, Andy Berndt, Noam Shazeer, Oriol Vinyals, Burak Gokturk, Amin Vahdat, Katherine Chou, Avinatan Hassidim, Koray Kavukcuoglu, Pushmeet Kohli, Yossi Matias, James Manyika, Jeff Dean and Demis Hassabis for their support.