用头发制成的牙膏,能自然修复牙齿根部。
Toothpaste made with keratin may protect and repair damaged teeth: study

原始链接: https://www.kcl.ac.uk/news/toothpaste-made-from-hair-provides-natural-root-to-repair-teeth

## 基于头发的牙膏:潜在的牙科革命 伦敦国王学院的科学家们发现,角蛋白(一种存在于头发、皮肤和羊毛中的蛋白质)可以有效修复牙釉质并阻止早期龋齿——这一过程目前只能被氟化物减缓。与无法再生的牙釉质不同,角蛋白与唾液相互作用时会形成保护性的、类似晶体的涂层,模仿天然牙釉质结构并封闭神经通道以减少敏感度。 这一突破为传统的、通常有毒的牙科树脂提供了一种可持续的替代方案。角蛋白来源于生物废弃物,促进循环经济和环保医疗保健。该疗法可能在2-3年内作为日常牙膏或专业应用的凝胶问世。 研究人员认为,这项技术代表着再生牙科领域的重要一步,有可能使用人体自身的材料恢复生物功能,从而带来更强健、更健康的笑容。

## 角蛋白牙膏:牙齿修复的潜在突破 一项新研究表明,将角蛋白(头发中的蛋白质)加入牙膏中,可以保护甚至*修复*受损的牙齿。与主要减缓牙釉质腐蚀的现有氟化物治疗方法不同,这种基于角蛋白的方法旨在模拟牙釉质的自然结构,提供一种潜在的再生解决方案。 Hacker News上的讨论显示出细微之处:这种效果似乎是一种保护涂层,而不是真正的牙釉质再生。一些评论者分享了使用含有Novamin的类似产品的积极体验,后者也能形成保护层,而另一些人则质疑营销炒作。人们对Novamin的有效性提出了担忧,有资料来源指出需要更严格的临床试验。 潜在的更快上市时间(2-3年)令人鼓舞,但成本效益和可扩展性仍然存在疑问。对话还涉及更广泛的牙齿健康问题,包括饮食的影响、纳米羟基磷灰石的有效性以及历史上的牙科实践。总之,虽然令人兴奋,但这项研究仍处于早期阶段,需要进一步验证。
相关文章

原文

Toothpaste made from your own hair may offer a sustainable and clinically effective way to protect and repair damaged teeth.

In a new study published today, scientists discovered that keratin, a protein found in hair, skin and wool, can repair tooth enamel and stop early stages of decay.

The King’s College London team of scientists discovered that keratin produces a protective coating that mimics the structure and function of natural enamel when it comes into contact with minerals in saliva.

Unlike bones and hair, enamel does not regenerate, once it is lost, it’s gone forever.

Dr Sherif Elsharkawy, senior author and consultant in prosthodontics at King’s College London

Acidic foods and drinks, poor oral hygiene, and ageing all contribute to enamel erosion and decay, leading to tooth sensitivity, pain and eventually tooth loss.

While fluoride toothpastes are currently used to slow this process, keratin-based treatments were found to stop it completely. Keratin forms a dense mineral layer that protects the tooth and seals off exposed nerve channels that cause sensitivity, offering both structural and symptomatic relief.

The treatment could be delivered through a toothpaste for daily use or as a professionally applied gel, similar to nail varnish, for more targeted repair. The team is already exploring pathways for clinical application and believes that keratin-based enamel regeneration could be made available to the public within the next two to three years.

In their study, published in Advanced Healthcare Materials, the scientists extracted keratin from wool. They discovered that when keratin is applied to the tooth surface and comes into contact with the minerals naturally present in saliva, it forms a highly organised, crystal-like scaffold that mimics the structure and function of natural enamel.

Over time, this scaffold continues to attract calcium and phosphate ions, leading to the growth of a protective enamel-like coating around the tooth. This marks a significant step forward in regenerative dentistry.

Animation graphic of toothpaste made of hair

Sara Gamea, PhD researcher at King’s College London and first author of the study, added: “Keratin offers a transformative alternative to current dental treatments. Not only is it sustainably sourced from biological waste materials like hair and skin, it also eliminates the need for traditional plastic resins, commonly used in restorative dentistry, which are toxic and less durable. Keratin also looks much more natural than these treatments, as it can more closely match the colour of the original tooth.”

As concerns grow over the sustainability of healthcare materials and long-term fluoride use, this discovery positions keratin as a leading candidate for future dental care. The research also aligns with broader efforts to embrace circular, waste-to-health innovations, transforming what would otherwise be discarded into a valuable clinical resource.

Sara Gamea said: “This technology bridges the gap between biology and dentistry, providing an eco-friendly biomaterial that mirrors natural processes.”

Dr Elsharkawy concluded: “We are entering an exciting era where biotechnology allows us to not just treat symptoms but restore biological function using the body’s own materials. With further development and the right industry partnerships, we may soon be growing stronger, healthier smiles from something as simple as a haircut.”

联系我们 contact @ memedata.com