终于,真正的蓝色玫瑰问世了
Finally, A True Blue Rose Exists

原始链接: https://www.sciencenews.org/article/true-blue-rose-pigment-copigment

多年来,人们一直认为“纯蓝色”玫瑰是不可能实现的,因为玫瑰缺乏产生蓝色素所需的酶,也缺少稳定蓝色素的必要“辅助色素”。尽管三得利全球创新中心的研发人员早在2004年就尝试培育蓝色玫瑰,但最终结果仅呈淡紫色。 近期,科学家们取得了一项突破,他们将来自其他蓝色花卉品种(风铃草、蝴蝶草和龙胆)的四个基因植入玫瑰中。这一改造使玫瑰能够同时产生蓝色素锦葵色素以及被称为“辅助色素”的特定无色分子。这些辅助分子能够稳定色素,从而形成一种独特的“紫蓝色”。 研究人员证实,辅助色素的含量越高,蓝色就越深。这些基因工程玫瑰表现稳定,在七年的温室测试和三年的野外生长中均保持了蓝色。目前,该团队正继续改进方法,以进一步增强蓝色的浓度。

一份近期报告声称培育出了“真正的蓝玫瑰”,这一话题再次在 Hacker News 上引发热议。参与讨论的人士指出,三得利(Suntory)研发的这种花卉更准确的描述是“紫蓝色”,而非鲜艳的纯蓝色。 这项技术成就依赖于复杂的基因剪接——即整合飞燕草和龙胆草等蓝色花卉的基因特征——并利用“辅色素沉着”技术来影响颜色。用户们提到,这些玫瑰是数十年研究的成果,建立在三得利 2004 年推出的“蓝色妖姬”(Applause)玫瑰基础之上。 讨论还涉及了生物色彩表达所面临的挑战,许多人指出,无论是在自然界还是摄影中,蓝色都以难以捕捉而著称。虽然一些评论者对这种营销持怀疑态度,将其颜色比作“病态的紫色”,但也有人支持这一科学尝试。他们认为,此类研究是生物技术极具价值的概念验证,推动了基因改造技术的发展,其应用范围远超花卉栽培领域。总之,人们普遍认为,尽管完美的“蓝色”仍难以实现,但这项研究在园艺科学领域已是一个意义重大且微妙的里程碑。
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原文

This development could change poetry forever. Roses are red and now they’re also blue.

True blue roses were once thought impossible. Roses can make red and yellow pigments but don’t have an enzyme needed to make blue pigments. At least they didn’t until 2004, when researchers at the Suntory Global Innovation Center in Kyoto, Japan, genetically modified a rose to produce blue pigments. The team inserted the gene for an enzyme that can produce a blue pigment called delphinidin. But those roses were purplish, suggesting it takes more than blue pigment to make flowers blue.

Naturally blue flowers, such as irises, make blue pigments like delphinidin. But they also need almost colorless “co-pigment” molecules called flavone C-glycosides to create their blue hue. Those helper molecules stabilize pigments and make them appear deeper blue. Roses also lack genes for making the co-pigments.

This time, Suntory researchers inserted four genes from other blue flower species into a light pink rose. A gene from Canterbury bells (Campanula medium) allowed the engineered roses to produce multiple blue pigments. Two genes from wishbone flowers (Torenia x hybrida) and one from clustered gentian (Gentiana triflora) made enzymes that produce the colorless helper molecules. The combination of the blue pigment malvidin with a helper called isoorientin made bluer flowers than roses producing only delphinidin, the company announced August 25 at the 32nd International Horticultural Congress in Kyoto. The higher the level of co-pigments in the petals, the bluer the flowers, the researchers found.

Roses making the co-pigments are rated as violet blue based on a flower color chart. The rose bushes continued to produce blue flowers for seven years in greenhouse tests in Japan and three years growing in fields in Colombia.

The achievement is sweet. And the team hopes to further enhance the hue.

Tina Hesman Saey is the senior staff writer and reports on molecular biology. She has a Ph.D. in molecular genetics from Washington University in St. Louis and a master’s degree in science journalism from Boston University.

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